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Senolytic Peptide FOXO4-DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes

Autologous chondrocyte implantation (ACI) is a procedure used to treat articular cartilage injuries and prevent the onset of post-traumatic osteoarthritis. In vitro expansion of chondrocytes, a necessary step in ACI, results in the generation of senescent cells that adversely affect the quality and...

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Bibliografiske detaljer
Principais autores: Yuzhao Huang, Yuchen He, Meagan J. Makarcyzk, Hang Lin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-04-01
Serier:Frontiers in Bioengineering and Biotechnology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fbioe.2021.677576/full
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