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Hypermethylated LTR retrotransposon exhibits enhancer activity

LTR retrotransposons are repetitive DNA elements comprising ∼10% of the human genome. They are silenced by hypermethylation of cytosines in CpG dinucleotides and are considered parasitic DNA serving no useful function for the host genome. However, hypermethylated LTRs contain enhancer and promoter s...

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Bibliografische Detailangaben
Hauptverfasser: Tianxiang Hu, Xingguo Zhu, Wenhu Pi, Miao Yu, Huidong Shi, Dorothy Tuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis Group 2017-03-01
Schriftenreihe:Epigenetics
Schlagworte:
Online-Zugang:http://dx.doi.org/10.1080/15592294.2017.1289300
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