Clinical implications of 10-formyltetrahydrofolate dehydrogenase expression in hormone receptor-positive breast cancer

ObjectiveALDH1L1, a key enzyme in folate metabolism, has been implicated in various cancers, but the clinical significance of its expression in breast cancer remains unclear.MethodsWe analyzed three cohorts from Seoul National University Hospital: (i) 41 non-matched patient samples (23 samples from...

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Hauptverfasser:	Han Suk Ryu, Amira A. Abdellatef, Da Sol Kim, Ilias P. Nikas, Sergey A. Krupenko
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2026-05-01
Schriftenreihe:	Frontiers in Oncology
Schlagworte:	ALDH1L1 biomarker hormone receptor-breast cancer prognosis tumor suppressor gene
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1838093/full
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