Pharmacological Evaluation of active compounds in papaya associated with thrombocytopenia inhibition in dengue patients through in silico approaches

Abstract This study investigates the therapeutic potential of five natural compounds from Carica papaya — olean-12-ene, quercetin, apigenin, luteolin and kaempferol — against dengue virus (DENV) using a multi-faceted in silico approach. Quantum chemical analysis using density functional theory (DFT)...

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Bibliografische Detailangaben

Hauptverfasser:	Md. Anisur Rahman, Guilherme Bastos Alves, Gabriel Vinícius Rolim Silva, Aamal A. Al-Mutairi, Shahina Akter, Endalamaw Yihune, Magdi E. A. Zaki, Jonas Ivan Nobre Oliveira
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-07-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Natural products Dengue virus In Silico drug discovery Molecular Docking ADMET DFT
Online-Zugang:	https://doi.org/10.1038/s41598-025-09835-w
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