Early-onset impairment of the ubiquitin-proteasome system in dopaminergic neurons caused by α-synuclein

Abstract Parkinson’s disease is a progressive neurodegenerative disorder characterised by the accumulation of misfolded α-synuclein in selected brain regions, including the substantia nigra pars compacta (SNpc), where marked loss of dopaminergic neurons is also observed. Yet, the relationship betwee...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Chris McKinnon, Mitchell L. De Snoo, Elise Gondard, Clemens Neudorfer, Hien Chau, Sophie G. Ngana, Darren M. O’Hara, Jonathan M. Brotchie, James B. Koprich, Andres M. Lozano, Lorraine V. Kalia, Suneil K. Kalia
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2020-02-01
Σειρά:	Acta Neuropathologica Communications
Θέματα:	Parkinson’s disease Ubiquitin-proteasome system α-Synuclein Neurodegeneration
Διαθέσιμο Online:	https://doi.org/10.1186/s40478-020-0894-0
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