Excellent removal of knob-into-hole bispecific antibody byproducts and impurities in a single-capture chromatography
Abstract Bispecific antibodies (bsAbs) are therapeutically promising due to their ability to bind to two different antigens. However, the bsAb byproducts and impurities, including mispaired homodimers, half-antibodies, light chain mispairings, antibody fragments and high levels of high molecular wei...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
SpringerOpen
2022-07-01
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| Reeks: | Bioresources and Bioprocessing |
| Onderwerpen: | |
| Online toegang: | https://doi.org/10.1186/s40643-022-00562-y |
| Tags: |
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