Microneedle-based sustained release delivery of TNF-α/IL-6R dual-specific fenobody alleviates inflammation and promotes bone regeneration in rheumatoid arthritis rat model

Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease characterized by inflammatory imbalance. The cytokine-targeted therapy is a non-traditional form of RA treatment that is mighty effective but poses the challenge of pharmaceutical storage conditions, professional injection, frequent...

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Автори:	Xiqian Zhang, Jian Chen, Na Huang, Qi Chen, Muhammad Asad Farooq, Ping Ouyang, Kaisong Huang, Kangsheng Liao, Wanjun He, Kai Cui, Dan Jiang, Guangxian Xu
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Elsevier 2025-08-01
Серія:	Materials Today Bio
Предмети:	Rheumatoid arthritis TNF-α IL-6R Fenobody GelMA microneedle
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S2590006425004752
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