The CLC-5 2Cl-/H+ exchange transporter in endosomal function and Dent’s disease.
CLC-5 plays a critical role in the process of endocytosis in the proximal tubule of the kidney and mutations that alter protein function are the cause of Dent’s I disease. In this X-linked disorder impaired reabsorption results in the wasting of calcium and low molecular weight protein to the urine,...
Guardado en:
| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2012-11-01
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| Colección: | Frontiers in Physiology |
| Materias: | |
| Acceso en línea: | http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00449/full |
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