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IGF2BP3 promotes the muscle invasion of bladder cancer via PPARγ dysregulation

Abstract Bladder cancer (BC) is a common urinary-tract malignancy that, once it progresses to the muscle‐invasive form (MIBC), adopts a markedly more aggressive behavior and is linked to significantly poorer patient outcomes. Despite extensive investigation, the molecular drivers of MIBC progression...

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Principais autores: Jing-yi Cao, Hua Peng, Guang-yue Wang, Ping-An Chang, Wen-Tao Yao, Qian Wang, Jie-Zhou, Gui-hua Zhang, Heng Wang, Jia-Cheng Wu, Sha-Sha Li, Quan-lan Gao, Chang-song Pei, Qi-chao Wang
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2026-03-01
Serier:Discover Oncology
Fag:
Bladder cancer
IGF2BP3
Muscle-invasive
PPARgamma
Online adgang:https://doi.org/10.1007/s12672-026-04648-3
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