Evolutionary analyses of polymeric immunoglobulin receptor (pIgR) in the mammals reveals an outstanding mutation rate in the lagomorphs

BackgroundThe transcytosis of polymeric immunoglobulins, IgA and IgM, across the epithelial barrier to the luminal side of mucosal tissues is mediated by the polymeric immunoglobulin receptor (pIgR). At the luminal side the extracellular ligand binding region of pIgR, the secretory component (SC), i...

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Главные авторы:	Fabiana Neves, Patrícia de Sousa-Pereira, José Melo-Ferreira, Pedro J. Esteves, Ana Pinheiro
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2022-11-01
Серии:	Frontiers in Immunology
Предметы:	evolution european rabbit positive selection immune system fc receptors
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1009387/full
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