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Angiopoietin-like protein 4 (ANGPTL4) is an inhibitor of endothelial lipase (EL) while the ANGPTL4/8 complex has reduced EL-inhibitory activity

We previously demonstrated that angiopoietin-like protein 8 (ANGPTL8) forms ANGPTL3/8 and ANGPTL4/8 complexes that increase with feeding to direct fatty acids (FA) toward adipose tissue through differential modulation of lipoprotein lipase (LPL) activity. Each complex correlated inversely with high...

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Hoofdauteurs: Yan Q. Chen, Thomas G. Pottanat, Robert W. Siegel, Mariam Ehsani, Yue-Wei Qian, Robert J. Konrad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2021-09-01
Reeks:Heliyon
Onderwerpen:
Endothelial lipase
HDL
Triglycerides
Angiopoietin-like protein
Phospholipids
Postprandial state
Online toegang:http://www.sciencedirect.com/science/article/pii/S2405844021020016
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