Concomitant genetic alterations having greater impact on the clinical benefit of EGFR‐TKIs in EGFR‐mutant advanced NSCLC than BIM deletion polymorphism

Abstract Background In previous studies, the predictive role of BIM deletion polymorphism with respect to responses to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR‐TKIs) has been controversial. The potential reasons for these inconsistent findings were unknown. Methods Data from...

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Auteurs principaux:	Si‐Yang Liu, Jia‐Ying Zhou, Wen‐Feng Li, Hao Sun, Yi‐Chen Zhang, Hong‐Hong Yan, Zhi‐Hong Chen, Chun‐Xiang Chen, Jun‐Yi Ye, Jin‐Ji Yang, Qing Zhou, Xu‐Chao Zhang, Yi‐Long Wu
Format:	Artigo
Langue:	Inglês
Publié:	Wiley 2020-03-01
Collection:	Clinical and Translational Medicine
Sujets:	BIM deletion polymorphism concomitant genetic alterations EGFR‐TKIs next‐generation sequencing NSCLC
Accès en ligne:	https://doi.org/10.1002/ctm2.12
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