Two novel deep-sea sediment metagenome-derived esterases: residue 199 is the determinant of substrate specificity and preference

Abstract Background The deep-sea environment harbors a vast pool of novel enzymes. Owing to the limitations of cultivation, cultivation-independent has become an effective method for mining novel enzymes from the environment. Based on a deep-sea sediment metagenomics library, lipolytic-positive clon...

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Bibliografski detalji

Glavni autori:	Ying-Yi Huo, Shu-Ling Jian, Hong Cheng, Zhen Rong, Heng-Lin Cui, Xue-Wei Xu
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2018-01-01
Serija:	Microbial Cell Factories
Teme:	Metagenomics library Esterase Family IV Deep-sea Substrate-binding pocket Homology modeling
Online pristup:	http://link.springer.com/article/10.1186/s12934-018-0864-4
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