EV71 infection induces neurodegeneration via activating TLR7 signaling and IL-6 production.

As a neurotropic virus, human Enterovirus 71 (EV71) infection causes hand-foot-and-mouth disease (HFMD) and may develop severe neurological disorders in infants. Toll-like receptor 7 (TLR7) acts as an innate immune receptor and is also a death receptor in the central nervous system (CNS). However, t...

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Библиографические подробности

Главные авторы:	Zhen Luo, Rui Su, Wenbiao Wang, Yicong Liang, Xiaofeng Zeng, Muhammad Adnan Shereen, Nadia Bashir, Qi Zhang, Ling Zhao, Kailang Wu, Yingle Liu, Jianguo Wu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2019-11-01
Серии:	PLoS Pathogens
Online-ссылка:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008142&type=printable
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