miR-214 Attenuates Aortic Valve Calcification by Regulating Osteogenic Differentiation of Valvular Interstitial Cells

Calcific aortic valve disease (CAVD) is a common heart valve disease in aging populations, and aberrant osteogenic differentiation of valvular interstitial cells (VICs) plays a critical role in the pathogenesis of ectopic ossification of the aortic valve. miR-214 has been validated to be involved in...

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Detalhes bibliográficos

Principais autores:	Ning Li, Yifan Bai, Guangwei Zhou, Ye Ma, Mengwei Tan, Fan Qiao, Xin Li, Ming Shen, Xiaowei Song, Xianxian Zhao, Xiaohong Liu, Zhiyun Xu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2020-12-01
coleção:	Molecular Therapy: Nucleic Acids
Assuntos:	microRNA-214 calcific aortic valve disease valvular interstitial cells ATF4 Sp7
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2162253120303280
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