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Generation of Otic Lineages from Integration-Free Human-Induced Pluripotent Stem Cells Reprogrammed by mRNAs

Damage to the sensory hair cells and the spiral ganglion neurons of the cochlea leads to deafness. Induced pluripotent stem cells (iPSCs) are a promising tool to regenerate the cells in the inner ear that have been affected by pathology or have been lost. To facilitate the clinical application of iP...

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Váldodahkkit: Sarah L. Boddy, Ricardo Romero-Guevara, Ae-Ri Ji, Christian Unger, Laura Corns, Walter Marcotti, Marcelo N. Rivolta
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Wiley 2020-01-01
Ráidu:Stem Cells International
Liŋkkat:http://dx.doi.org/10.1155/2020/3692937
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