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Incorporating Patient Perspectives into a Composite Score for Measuring Disease Progression in Spinocerebellar Ataxia (SCA)

Abstract Introduction The spinocerebellar ataxia composite score (SCACOMS) comprises items from the functional Scale for the Assessment and Rating of Ataxia (f-SARA) and the Clinician Global Impression of Change (CGI-C). In the derivation of SCACOMS, weights reflecting 1-year responsiveness were ass...

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Principais autores: Michele H. Potashman, Basia M. Rogula, Lauren C. Powell, Ellen E. Korol, Sam P. Dickson, Suzanne Hendrix, Maggie Heinrich, Katja Rudell, Linda Abetz-Webb, Melissa W. Beiner, Vlad Coric, Liana S. Rosenthal, Susan L. Perlman, Jeremy D. Schmahmann, Gil L’Italien
Formato: Artigo
Idioma:Inglês
Publicado em: Adis, Springer Healthcare 2026-02-01
coleção:Neurology and Therapy
Assuntos:
Spinocerebellar ataxia
Composite score
Patient perspective
Patient preference
PLS regression
Acesso em linha:https://doi.org/10.1007/s40120-026-00891-6
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