Glycyrrhizin (GLY) and glycyrrhetinic acid (GA) as potential multi-target antimicrobials: mechanisms, biofilm disruption, and synergy against drug-resistant pathogens

Antimicrobial resistance (AMR) is a major global health challenge of the 21st century, driven by multidrug-resistant pathogens, persistent biofilm-associated infections, and a dwindling pipeline of new antibiotics. These limitations have renewed interest in natural products with multi-target antimic...

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Autore principale:	Kumar D. Gahlot
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-06-01
Serie:	Frontiers in Microbiology
Soggetti:	biofilms glycyrrhetinic acid (GA) glycyrrhizin (GLY) host–pathogen interactions multi-target antimicrobials natural products
Accesso online:	https://www.frontiersin.org/articles/10.3389/fmicb.2026.1861692/full
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