Molecular Mechanism of Hippo–YAP1/TAZ Pathway in Heart Development, Disease, and Regeneration

The Hippo–YAP1/TAZ pathway is a highly conserved central mechanism that controls organ size through the regulation of cell proliferation and other physical attributes of cells. The transcriptional factors Yes-associated protein 1 (YAP1) and PDZ-binding motif (TAZ) act as downstream effectors of the...

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Autori principali:	Xiaoqing Chen, Yilang Li, Jiandong Luo, Ning Hou
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2020-04-01
Serie:	Frontiers in Physiology
Soggetti:	YAP1/TAZ Hippo pathway post-translational modification heart development cardiac disease regeneration
Accesso online:	https://www.frontiersin.org/article/10.3389/fphys.2020.00389/full
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