Pharmacokinetics/Pharmacodynamics-Based Repositioning of Cefmetazole and Flomoxef in Extended-Spectrum β-Lactamase-Producing Enterobacterales Treatment: An Injectable Carbapenem-Sparing and Outpatient Strategy

Infections caused by extended-spectrum β-lactamase-producing Enterobacterales (ESBL-Es) pose a significant global threat with notable increases in prevalence worldwide. Carbapenems are often used as the first line of treatment. However, their overuse accelerates resistance development, highlighting...

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Päätekijät:	Takahiro Kato, Yusuke Yagi, Takumi Maruyama, Yukihiro Hamada
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2025-07-01
Sarja:	Antibiotics
Aiheet:	extended-spectrum β-lactamase-producing Enterobacterales carbapenem-sparing cefmetazole flomoxef pharmacokinetics/pharmacodynamics outpatient setting
Linkit:	https://www.mdpi.com/2079-6382/14/8/737
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