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Identification and verification of a polyamine metabolism-related gene signature for predicting prognosis and immune infiltration in osteosarcoma

Abstract Background Although an established correlation exists between tumor cell proliferation and elevated polyamine levels, research on polyamine metabolism in osteosarcoma (OS) remains limited. This study aimed to identify polyamine metabolism-related genes (PMRGs) associated with OS prognosis a...

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Hlavní autoři: Shuo Qiu, Chen Tan, Dongdong Cheng, Qingcheng Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-05-01
Edice:Journal of Orthopaedic Surgery and Research
Témata:
Osteosarcoma
Polyamine metabolism
Prognostic genes
Immune infiltration
Risk model
On-line přístup:https://doi.org/10.1186/s13018-025-05716-0
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