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Lgr5 marks stem/progenitor cells contributing to epithelial and muscle development in the mouse esophagus

Abstract The existence and function of Lgr5+ cells within the developing esophagus remains unknown. Here, we document multiple discrete Lgr5+ populations in the developing mouse esophagus, predominantly within nascent epithelial and external muscle layers. Lgr5 expression initially emerges in the de...

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Autori principali: Lana Kostic, Carly Leung, Katzrin Ahmad Murad, Snezhina Kancheva, Stefano Perna, Bernett Lee, Nick Barker
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2024-08-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-024-51559-4
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