SUN-MKL1 Crosstalk Regulates Nuclear Deformation and Fast Motility of Breast Carcinoma Cells in Fibrillar ECM Microenvironment

Aligned collagen fibers provide topography for the rapid migration of single tumor cells (streaming migration) to invade the surrounding stroma, move within tumor nests towards blood vessels to intravasate and form distant metastases. Mechanisms of tumor cell motility have been studied extensively i...

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Autors principals:	Ved P. Sharma, James Williams, Edison Leung, Joe Sanders, Robert Eddy, James Castracane, Maja H. Oktay, David Entenberg, John S. Condeelis
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2021-06-01
Col·lecció:	Cells
Matèries:	breast cancer invasion and metastasis in vivo tumor cell motility nuclear deformation LINC complex SRF-MKL1 signaling
Accés en línia:	https://www.mdpi.com/2073-4409/10/6/1549
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