Mechanism study of exercise intervention on circadian disruption in Alzheimer’s disease

Alzheimer’s disease (AD) induces profound circadian disruption—characterized by suprachiasmatic nucleus (SCN) degeneration, Aβ and tau pathology, and aberrant melatonin secretion which results in fragmented sleep–wake cycles and cognitive decline. Emerging evidence indicates that exercise significan...

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Opis bibliograficzny

Główni autorzy:	Mingzheng Zhang, Lei Shi, Xiangqi Meng, Yahong Dong, Yinjie Sun, Qiheng Qian, Qiguan Jin
Format:	Artigo
Język:	Inglês
Wydane:	Frontiers Media S.A. 2025-12-01
Seria:	Frontiers in Neuroscience
Hasła przedmiotowe:	Alzheimer’s disease circadian rhythm disruption exercise intervention Aβ clearance melatonin rhythm core clock genes
Dostęp online:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1696673/full
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