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Spata19 Inactivation as a Cause of Oligospermia

Background: Spermatogenesis associated 19 (Spata19) was introduced as a testis-specific gene that was probably involved in spermatogenesis cell apoptosis. Therefore, this study aimed to investigate the effect of Spata19 inactivation on sperm count. Materials and Methods: We generated global Spata19...

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Principais autores: Mahsa Zargar, Abbas Jamshidizad, Aidin Rahim-Tayefeh, Ehsan Hashemi, Sasan Shabani, Mehdi Shamsara, Mohammad Hossein Modarressi
Formato: Artigo
Idioma:Inglês
Publicado em: Mazandaran University of Medical Sciences and Health Services 2021-02-01
coleção:Research in Molecular Medicine
Assuntos:
spermatogenesis associated 19 (spata19)
crispr/cas9 nickase
global knockout mice
oligospermia
infertility
spermatogenesis
outbred mice
Acesso em linha:http://rmm.mazums.ac.ir/article-1-402-en.html
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