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Leonurine inhibits cardiomyocyte pyroptosis to attenuate cardiac fibrosis via the TGF-β/Smad2 signalling pathway.

Cardiac fibrosis is a common cause of most cardiovascular diseases. Leonurine, an alkaloid from Herba leonuri, had been indicated to treat cardiovascular diseases due to its cardioprotective effects. Recently, pyroptosis, a programmed form of cell death that releases inflammatory factors, has been s...

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Bibliografische gegevens
Hoofdauteurs: Zhaoyi Li, Keyuan Chen, Yi Zhun Zhu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2022-01-01
Reeks:PLoS ONE
Online toegang:https://doi.org/10.1371/journal.pone.0275258
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