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Transcriptional profiling links unique human macrophage phenotypes to the growth of intracellular Salmonella enterica serovar Typhi

Abstract Macrophages provide a crucial environment for Salmonella enterica serovar Typhi (S. Typhi) to multiply during typhoid fever, yet our understanding of how human macrophages and S. Typhi interact remains limited. In this study, we delve into the dynamics of S. Typhi replication within human m...

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Bibliographic Details
Main Authors: Ruth Schade, Daniel S. C. Butler, Joy A. McKenna, Blanda Di Luccia, Vida Shokoohi, Meagan Hamblin, Trung H. M. Pham, Denise M. Monack
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2024-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-63588-6
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