Ribosome Biogenesis as a Putative Bottleneck to Skeletal Muscle Hypertrophy: Mechanisms, Human Evidence, and Practical Modulators

Background: Skeletal muscle hypertrophy has traditionally been attributed to transient spikes in translational efficiency governed by the mTORC1 signaling cascade. However, contemporary molecular evidence reveals that sustained macroscopic growth is strongly associated with the physical expansion of...

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Hlavní autoři:	Mario Muñoz López, José Francisco López-Gil, Xabier Ramírez de la piscina Viúdez, Eneko Baz-Valle, José Francisco Tornero Aguilera
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2026-06-01
Edice:	Cells
Témata:	ribosome biogenesis skeletal muscle hypertrophy translational capacity RNA Polymerase I nucleolus mechanotransduction
On-line přístup:	https://www.mdpi.com/2073-4409/15/11/1041
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