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Adipocyte pyroptosis occurs in omental tumor microenvironment and is associated with chemoresistance of ovarian cancer

Abstract Background Ovarian carcinoma (OC) is a fatal malignancy, with most patients experiencing recurrence and resistance to chemotherapy. In contrast to hematogenous metastasizing tumors, ovarian cancer cells disseminate within the peritoneal cavity, especially the omentum. Previously, we reporte...

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Principais autores: Chang-Ni Lin, Yu-Ling Liang, Hsing-Fen Tsai, Pei-Ying Wu, Lan-Yin Huang, Yu-Han Lin, Chieh-Yi Kang, Chao-Ling Yao, Meng-Ru Shen, Keng-Fu Hsu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-06-01
Serier:Journal of Biomedical Science
Fag:
Ovarian cancer
Omentum metastasis
Inflammation
Adipocyte pyroptosis
Chemoresistance
Online adgang:https://doi.org/10.1186/s12929-024-01051-4
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