Oral microbiome dysbiosis in cryptogenic ischemic stroke patients with high-risk patent foramen ovale

Abstract Patent foramen ovale (PFO) is the most common congenital heart abnormality of foetal origin and has been associated with cryptogenic ischemic stroke (CIS) through several mechanisms, with most theories supporting paradoxical embolism. Other possible but unknown contributing factors, such as...

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Detalhes bibliográficos

Principais autores:	Muhammed Manzoor, Jaakko Leskelä, Milla Pietiäinen, Nicolas Martinez-Majander, Eija Könönen, Juha Sinisalo, Jukka Putaala, Pirkko J. Pussinen, Susanna Paju
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-04-01
coleção:	Scientific Reports
Assuntos:	Cryptogenic ischemic stroke Oral microbiome Patent foramen ovale Stroke Paradoxical embolism Saliva
Acesso em linha:	https://doi.org/10.1038/s41598-025-95728-x
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