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Proteomic Profiling of PTEN Inhibition on Periodontal Ligament Stem Cells

Objective: Phosphatase and tensin homolog (PTEN) is a critical regulator of cell proliferation, differentiation, and inflammatory balance. However, its downstream proteomic effects in periodontal ligament stem cells (PDLSCs) remain poorly understood. This study aimed to elucidate the proteomic alter...

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Principais autores: Suphalak Phothichailert, Nunthawan Nowwarote, Chatvadee Kornsuthisopon, Shinya Murakami, Supreda Suphanantachat Srithanyarat, Thanaphum Osathanon
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2026-06-01
Series:International Dental Journal
Assuntos:
PTEN inhibitor
VO-OHpic
Mesenchymal stem cells
Proteomics
MAPK cascade
Periodontal regeneration
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0020653926000894
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