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Generation of RAG2 Knockout Immune-Deficient Miniature Pigs

Recombination-activating genes (RAGs) play a crucial role in the V(D)J recombination process and the development of immune cells. The development of the immune system and its mechanisms in pigs exhibit greater similarity to those of humans compared to other animals, thus rendering pigs a valuable to...

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Principais autores: Jing Wang, Feiyan Zhu, Deling Jiao, Chang Yang, Junqi Wang, Fengchong Wang, Heng Zhao, Hong-Jiang Wei, Hong-Ye Zhao
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-09-01
Serier:Animals
Fag:
RAG2
knockout
severe immunodeficiency
pigs
Online adgang:https://www.mdpi.com/2076-2615/14/17/2597
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