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NAC, tiron and trolox impair survival of cell cultures containing glioblastoma tumorigenic initiating cells by inhibition of cell cycle progression.

Reactive oxygen species (ROS) are metabolism by-products that may act as signaling molecules to sustain tumor growth. Antioxidants have been used to impair cancer cell survival. Our goal was to determine the mechanisms involved in the response to antioxidants of a human cell culture (PT4) containing...

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Principais autores: Massimiliano Monticone, Razieh Taherian, Sara Stigliani, Elisa Carra, Stefano Monteghirfo, Luca Longo, Antonio Daga, Mariella Dono, Simona Zupo, Walter Giaretti, Patrizio Castagnola
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2014-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090085&type=printable
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