Iron Status May Not Affect Amyotrophic Lateral Sclerosis: A Mendelian Randomization Study

BackgroundObservational studies have shown an association of increased iron status with a higher risk of amyotrophic lateral sclerosis (ALS). Iron status might be a novel target for ALS prevention if a causal relationship exists. We aimed to reveal the causality between iron status and ALS incidence...

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Autori principali:	Jiahao Cai, Xiong Chen, Hongxuan Wang, Zixin Wei, Mei Li, Xiaoming Rong, Xiangpen Li, Ying Peng
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-03-01
Serie:	Frontiers in Genetics
Soggetti:	iron neurodegeneration amyotrophic lateral sclerosis Mendelian randomization causality
Accesso online:	https://www.frontiersin.org/articles/10.3389/fgene.2021.617245/full
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