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Diagnostic accuracy and practicability of the VISITECT® advanced HIV disease CD4 test compared to the Partec® CyFlow Counter II for CD4 enumeration in Nigeria’s HIV program

Abstract We evaluated the diagnostic performance and practicability of the VISITECT® CD4 Lateral Flow Assay for identifying advanced HIV disease (AHD) across 13 facilities in Nigeria. In two phases, 468 participants were tested with VISITECT® CD4 and Partec® CyFlow. VISITECT® CD4 achieved a sensitiv...

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Principais autores: Justin Onyebuchi Nwofe, Daniel Chinenyeike Offie, Izuchukwu Ibeagha, Christian Okechukwu Ugwu, Emmanuel Adewale Ojo, David Segun Adeniyi, Daniel Oguh, Adeola Awolola, Olabamji Samuel Osho, Patrick Chike Okonkwo, Adebola Mary Onyenike, Isaac Onyebuchi Okohu, Oyewale Oguntade, Laura Madukaji, Olatunde James Kehinde, Anthony Ani, Ada Immaculata Chinweuba, Josephine Okemutie Omo-Emmanuel, Daniel Ogbuagu, Femi Emmanuel Owolagba, Eke Ofuche
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-01-01
Serier:AIDS Research and Therapy
Fag:
HIV
Advanced HIV disease
CD4 testing
Point-of-care diagnostics
VISITECT
Flow cytometry
Online adgang:https://doi.org/10.1186/s12981-026-00851-y
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