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Pyocyanin-enhanced neutrophil extracellular trap formation requires the NADPH oxidase.

Beyond intracellular killing, a novel neutrophil-based antimicrobial mechanism has been recently discovered: entrapment and killing by neutrophil extracellular traps (NETs). NETs consist of extruded nuclear DNA webs decorated with granule proteins. Although NET formation is an important innate immun...

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Autori principali: Balázs Rada, Meghan A Jendrysik, Lan Pang, Craig P Hayes, Dae-Goon Yoo, Jonathan J Park, Samuel M Moskowitz, Harry L Malech, Thomas L Leto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0054205&type=printable
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