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Effect of chloroquine on reducing HIV-1 replication <it>in vitro </it>and the DC-SIGN mediated transfer of virus to CD4<sup>+ </sup>T-lymphocytes

<p>Abstract</p> <p>Background</p> <p>Chloroquine (CQ) has been shown to inhibit HIV-1 replication <it>in vitro </it>as well as <it>in vivo </it>and has been proposed to alter the glycosylation pattern of the gp120 envelope. These activities indicate that the compound can be used not only as an effec...

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Bibliographic Details
Main Authors: Paxton William A, Pollakis Georgios, Baan Elly, Naarding Marloes A
Format: Artigo
Language:Inglês
Published: BMC 2007-01-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/4/1/6
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