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The extracellular loop of the membrane permease VraG interacts with GraS to sense cationic antimicrobial peptides in Staphylococcus aureus.

Host defense proteins (HDPs), aka defensins, are a key part of the innate immune system that functions by inserting into the bacterial membranes to form pores to kill invading and colonizing microorganisms. To ensure survival, microorganism such as S. aureus has developed survival strategies to sens...

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Detalles Bibliográficos
Principais autores: Junho Cho, Stephen K Costa, Rachel M Wierzbicki, William F C Rigby, Ambrose L Cheung
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Pathogens
Acceso en liña:https://doi.org/10.1371/journal.ppat.1009338
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