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Is sickle cell disease-related neurotoxicity a systemic endotheliopathy?

The aim of the present article is to review the role of endothelial damage and dysfunction in the vaso-occlusive episodes associated with sickle cell disease (SCD). This inherited hematological disorder leads to irreversible damage of multiple organs through a wide variety of mechanisms, such as sic...

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Autori principali: Marta Palomo, Maribel Diaz-Ricart, Enric Carreras
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer Medknow Publications 2020-04-01
Serie:Hematology/Oncology and Stem Cell Therapy
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Accesso online:https://journals.lww.com/10.1016/j.hemonc.2019.12.005
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