Ethyl-2-oxo-2H-chromene-3-carboxylate exhibits anti-allergic effects by inhibiting IgE-mediated mast cell activation and passive cutaneous anaphylaxis in mice

Abstract An allergy is an exaggerated immune response to an otherwise harmless substance. These reactions are triggered largely by mast cell activation and the subsequent release of inflammatory mediators. Although current allergy therapies effectively relieve symptoms, they are generally accompanie...

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Detalhes bibliográficos

Principais autores:	Serim Lee, Moonsu Kim, Seong-Ah Shin, Sun Young Moon, Seyeon Choi, Minji Kim, Jun Hyuck Lee, Ui Joung Youn, Chang Sup Lee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2026-01-01
coleção:	Applied Biological Chemistry
Assuntos:	Inflammatory cytokines Passive cutaneous anaphylaxis Ethyl-2-oxo-2H-chromene-3-carboxylate (EtCC) Mast cells Allergy Histamine
Acesso em linha:	https://doi.org/10.1186/s13765-025-01074-x
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