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Succinylation: novel molecular mechanisms and prospects for targeted therapy in liver diseases

Succinylation is a novel post-translational modification involving the attachment of a negatively charged succinyl group to lysine residues, which fundamentally alters the structure and function of substrate proteins. The liver, the metabolic center of the body, is a critical target for succinylatio...

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Bibliographic Details
Main Authors: Jie Zhou, Xiaoling Tian, Yifang Zhou, Nianhua Tan, Bin Chen
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2026-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2026.1768199/full
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