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mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection

Summary: SARS-CoV-2 infection and vaccination elicit potent immune responses. Our study presents a comprehensive multimodal single-cell analysis of blood from COVID-19 patients and healthy volunteers receiving the SARS-CoV-2 vaccine and booster. We profiled immune responses via transcriptional analy...

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Principais autores: Ellie N. Ivanova, Jasmine Shwetar, Joseph C. Devlin, Terkild B. Buus, Sophie Gray-Gaillard, Akiko Koide, Amber Cornelius, Marie I. Samanovic, Alberto Herrera, Eleni P. Mimitou, Chenzhen Zhang, Trishala Karmacharya, Ludovic Desvignes, Niels Ødum, Peter Smibert, Robert J. Ulrich, Mark J. Mulligan, Shohei Koide, Kelly V. Ruggles, Ramin S. Herati, Sergei B. Koralov
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-12-01
Serier:iScience
Fag:
Immunology
Immune response
Transcriptomics
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004223026494
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