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Safety profiles of IDH inhibitors: a pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database

Abstract Background With the increased use of isocitrate dehydrogenase (IDH) inhibitors in acute myeloid leukemia (AML) and cholangiocarcinoma, the toxicity of these drugs is a growing concern. This study aimed to evaluate the adverse events (AEs) of IDH inhibitors based on the Food and Drug Adminis...

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Autori principali: Ximu Sun, Han Zhou, Yanming Li, Yanhui Luo, Qixiang Guo, Yixin Sun, Chenguang Jia, Bin Wang, Maoquan Qin, Peng Guo
Natura: Artigo
Lingua:Inglês
Pubblicazione: SpringerOpen 2025-02-01
Serie:Future Journal of Pharmaceutical Sciences
Soggetti:
IDH inhibitors
Enasidenib
Ivosidenib
Olutasidenib
FAERS
Pharmacovigilance
Accesso online:https://doi.org/10.1186/s43094-025-00769-8
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