Chitinase 3-like-1 (CHI3L1) in the pathogenesis of epidermal growth factor receptor mutant non-small cell lung cancer

Non-small cell lung cancer (NSCLC) accounts for 85 % of all lung cancers. In NSCLC, 10–20 % of Caucasian patients and 30–50 % of Asian patients have tumors with activating mutations in the Epidermal Growth Factor Receptor (EGFR). A high percentage of these patients exhibit favorable responses to tre...

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Auteurs principaux:	Suchitra Kamle, Bing Ma, Gail Schor, Madison Bailey, Brianna Pham, Inyoung Cho, Hina Khan, Christopher Azzoli, Mara Hofstetter, Takayuki Sadanaga, Roy Herbst, Katerina Politi, Chun Geun Lee, Jack A. Elias
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2024-11-01
Collection:	Translational Oncology
Sujets:	Chitinase 3-like-1 Anti-CHI3L1 Epidermal growth factor receptor Epidermal growth factor STAT3 TKI drug resistance
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S1936523324002353
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