Construction and in vitro cytotoxicity assessment of T cell receptor-engineered T cells targeting human cytomegalovirus pp65495-503

Objective To construct T cell receptor-engineered T (TCR-T) cells targeting human cytomegalovirus (HCMV) pp65495-503, and to evaluate their in vitro cytotoxicity against HCMV-infected glioblastoma (GBM) cells. Methods Flow cytometry sorting was used to obtain HCMV pp65 antigen-specific T cells, and...

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Autor principal:	WANG Chen, WANG Bin, SHEN Wen, JIANG Shasha, QIAN Dongmeng
Format:	Artigo
Idioma:	Chinês
Publicat:	Editorial Office of Journal of Precision Medicine 2026-04-01
Col·lecció:	精准医学杂志
Matèries:	glioblastoma|cytomegalovirus infections|t-lymphocytes|receptors, antigen, t-cell|cell-and tissue-based therapy
Accés en línia:	https://jpmed.qdu.edu.cn/fileup/2096-529X/PDF/1778566277056-1788769780.pdf
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