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SUR1, newly expressed in astrocytes, mediates neuropathic pain in a mouse model of peripheral nerve injury

Background Neuropathic pain following peripheral nerve injury (PNI) is linked to neuroinflammation in the spinal cord marked by astrocyte activation and upregulation of interleukin 6 (IL - 6 ), chemokine (C-C motif) ligand 2 (CCL2) and chemokine (C-X-C motif) ligand 1 (CXCL1), with inhibition of eac...

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Autori principali: Orest Tsymbalyuk, Volodymyr Gerzanich, Aaida Mumtaz, Sanketh Andhavarapu, Svetlana Ivanova, Tapas K Makar, Charles A Sansur, Asaf Keller, Yumiko Nakamura, Joseph Bryan, J Marc Simard
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publishing 2021-03-01
Serie:Molecular Pain
Accesso online:https://doi.org/10.1177/17448069211006603
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