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Immune reactivity to Trypanosoma cruzi chimeric proteins for Chagas disease diagnosis in immigrants living in a non-endemic setting

Abstract Background Chronic Chagas Disease (CD) diagnosis is based on serological methods employing crude, semipurified or recombinant antigens, which may result in low sensitivity or cross-reactivity. To reduce these restrictions, we developed a strategy involving use of molecules containing repeti...

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Principais autores: Eva Dopico, Rodrigo Pimenta Del-Rei, Bertha Espinoza, Itziar Ubillos, Nilson Ivo Tonin Zanchin, Elena Sulleiro, Zaira Moure, Paola Alejandra Fiorani Celedon, Wayner Vieira Souza, Edimilson Domingos da Silva, Yara Miranda Gomes, Fred Luciano Neves Santos
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-03-01
Serier:BMC Infectious Diseases
Fag:
Chagas disease
Trypanosoma cruzi
Chimeric antigens
Immunoassay
Accuracy
Online adgang:http://link.springer.com/article/10.1186/s12879-019-3872-z
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