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Cryptocephal, the Drosophila melanogaster ATF4, is a specific coactivator for ecdysone receptor isoform B2.

The ecdysone receptor is a heterodimer of two nuclear receptors, the Ecdysone receptor (EcR) and Ultraspiracle (USP). In Drosophila melanogaster, three EcR isoforms share common DNA and ligand-binding domains, but these proteins differ in their most N-terminal regions and, consequently, in the activ...

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Autors principals: Sebastien A Gauthier, Eric VanHaaften, Lucy Cherbas, Peter Cherbas, Randall S Hewes
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC3415445?pdf=render
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