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Ferrous citrate up-regulates the NOS2 through nuclear translocation of NFκB induced by free radicals generation in mouse cerebral endothelial cells.

Previous studies indicate that the inducible nitric oxide synthase 2 (NOS2) of the brain vascular tissue in experimental subarachnoid hemorrhage (SAH) rats is a critical factor for inducing cerebral vasospasm. However, the underlying molecular mechanisms remain to be elucidated. Here, we applied fer...

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Hlavní autoři: Li-Ching Chen, Chin Hsu, Chuang Chin Chiueh, Wen-Sen Lee
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2012-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3460898?pdf=render
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