Reducing kidney uptake of radiolabelled exendin-4 using variants of the renally cleavable linker MVK
Abstract Background Peptidic radiotracers are preferentially excreted through the kidneys, which often results in high persistent renal retention of radioactivity, limiting or even preventing therapeutic clinical translation of these radiotracers. Exendin-4, which targets the glucagon-like-peptide 1...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
SpringerOpen
2023-09-01
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| Series: | EJNMMI Radiopharmacy and Chemistry |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1186/s41181-023-00206-2 |
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